Item
Blood protein concentrations in PRIORITY prior to randomization
- Title
- Blood protein concentrations in PRIORITY prior to randomization
- Description
-
The Early Detection of Diabetic Kidney Disease by Urinary Proteomics and
Subsequent Intervention with Spironolactone to Delay Progression (PRIORITY)
study was a multicentre, prospective, observational study with embedded
randomised controlled trial, which recruited people with type 2 diabetes, normal
urinary albumin excretion, and preserved renal function. All participants
(observational cohort) were tested with the CKD273 classifier and classified as high
risk (CKD273 classifier score >0·154) or low risk (≤0·154). Participants, who were
classified as high risk were entered into a randomised controlled trial and randomly
assigned (1:1) by use of an interactive web-response system, to receive
spironolactone 25 mg once daily or matched placebo (trial cohort).
The DC-ren project selected 79 patients from this cohort for in-depth molecular
characterization for baseline measurements of blood and urinary biomarker
candidates.
The here described data set comprises blood protein concentrations
determined by Luminex. Data from a total 79 study visits are available. - Subject
- Medicine, Health and Life Sciences
- Creator
- DC-ren Project
- Contributor
- Contact: SILVESTRI, Claudio
- Publisher
- Ca' Foscari University of Venice — Datarepository Unive
- Date
- 2025
- Identifier
- DOI: https://doi.org/10.71731/DATA_UNIVE/IRAL55
- Type
- Dataset
- Format
- JSON
- Source
- https://doi.org/10.71731/DATA_UNIVE/IRAL55
- Relation
- 1 file(s) in dataset
- Rights
-
All samples and data were obtained from individuals who gave written informed
consent specifically permitting their use for the clinical study's stated objectives.
Anyone seeking access to measurements (Data) obtained from the clinical study
samples must seek a data access agreement. In a first step the Project, in which the
Data will be used must be described and individuals who will have access to the data
must be identified. You must agree to only use the Data for the purpose of the
Project. Depending on type and area of research, additional institutional review
board approval may be necessary. - Educational Level
- Higher education | research
- Interactivity Type
- Active
- Item sets
- Ca' Foscari University of Venice